There are six category tabs underneath the options tab in the main menu of the game. When logged into a game session, this is reduced to five categories, removing the online tab, however, Session Settings can be accessed to change session and multiplayer settings.
Sets the autosave interval, 0 disables autosaves entirely. The amount of autosaves cannot be changed and is always 3
Break Notifications
On/Off
On
Unavailable as of a certain Update 3 patch, possibly 0.3.2.0 or 0.3.3.0. If enabled, a break notification would appear every 2 hours in a similar manner to autosave notifications.
Execute Build Step on Release
On/Off
Off
When enabled, buildings built with multiple clicks (such as Conveyor Poles) are now built with one click. Instead, holding down acts like the first click and letting go as the second
Automatic Clearance Separation
On/Off
Off
When enabled, buildings will be moved if they are built within the clearance of another building
Camera Movement Feedback Strength. (%)
0-150
100
Determines the strength of camera effects in Hyper Tubes
Explicit Pole Tilt by X-Axis
On/Off
Off
If enabled, Ctrl will set the vertical rotation instead of horizontal while constructing structures that can be rotated in multiple axes
Auto Save Notifications
On/Off
On
A notification is shown 10 seconds before each autosave and after the autosave is finished
Disable Seasonal Events
On/Off
Off
Title screen only. Removes seasonal events, such as FICSMAS, from the game
Enables directional subtitles for hostile creatures that show their movement, action, and attack sounds (e.g. Flying Crab Hatcher hatching or Hog footsteps)